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229 Complex machineries have been documented to be responsible for the release of calcium from cell organelles

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The MRS approach requires localizing the MR signal within a specific brain region, either by the exiting signal in a single rectangular volume of tissue (i.e., single voxels spectroscopy (SVS)) or by using gradients for spatial encoding over a large volume of tissue (i.e., multiple voxel shift imaging (CSI or MRSI))